Strange Brains and Case Studies

Introduction

Over the years, we have been compiling case studies in neuroscience to use for teaching (with help from Bill Meil). Below, is a list of bizarre things that might happen to your brain and associated case studies when possible. Wikipedia descriptions and links have been provided as an introduction to these strange brains and reference to popular science books are provided for case studies. Neither should be considered the paragon of truth and both should be read with some, if not heaps of skepticism. That said, case studies are a useful method of explication because, among other reasons, they add a humanistic element and provide a flavour for how incredibly interesting and strange the brain is that is often lacking in (dry) neuroscience textbooks.

Essential Reading

• Meil, W. M. (2007). The use of case studies in teaching undergraduate neuroscience. Journal of Undergraduate Neuroscience Education: JUNE: A Publication of FUN, Faculty for Undergraduate Neuroscience, 5(2), A53–A62.

Acalculia

• ‘An acquired impairment in which patients have difficulty performing simple mathematical tasks, such as adding, subtracting, multiplying and even simply stating which of two numbers is larger. Acalculia is distinguished from dyscalculia in that acalculia is acquired late in life due to neurological injury such as stroke, while dyscalculia is a specific developmental disorder first observed during the acquisition of mathematical knowledge.‘
  • From – http://en.wikipedia.org/wiki/Acalculia

Achromatopsia

• ‘Typically refers to an autosomal recessive congenital color vision disorder, the inability to perceive color AND to achieve satisfactory visual acuity at high light levels (typically exterior daylight).‘
  • From – http://en.wikipedia.org/wiki/Achromatopsia

• Case Study

  • Title – The Case of the Colorblind Painter
  • Notes – Tracks influence on case’s life and art
  • Reference – Sacks, O. (1995). An anthropologist on mars. New York, NY: Vintage Books.

Acromegaly

• ‘A syndrome that results when the pituitary gland produces excess growth hormone (hGH) after epiphyseal plate closure at puberty.‘
  • From – http://en.wikipedia.org/wiki/Agrammatism

• Case Study I

  • Title – Giants Among Men
  • Notes – Parallels Roman emperor and basketball player with excessive growth hormone release
  • Reference – Klawans, H. L. (1988). Toscanini’s fumble: And other tales of clinical neurology. Chicago, IL: Contemporary Books.

• Case Study II

  • Title – Primo Carnera: The Bigger They Are
  • Notes – Story of a boxer with excessive release of growth hormone
  • Reference – Klawans, H. L. (1996). Why Michael couldn’t hit: And other tales of the neurology of sports. New York, NY: W.H. Freeman.

Agrammatism

• ‘Agrammatism is a characteristic of non-fluent aphasia. Individuals with agrammatism present with speech that is characterized by containing mainly content words, with a lack of function words. For example, when asked to describe a picture of children playing in the park, the affected individual responds with, “trees.. children.. run.”‘
  • From – http://en.wikipedia.org/wiki/Agrammatism

Akinetopsia

• AKA – Motion Blindness
• ‘An extremely rare neuropsychological disorder in which a patient cannot perceive motion in his/her visual field, despite being able to see stationary objects without issue.‘
  • From – http://en.wikipedia.org/wiki/Motion_blindness

Alexia

• AKA – Text Blindness, Visual Aphasia, Word Blindness
• ‘Damage to the brain causes a patient to lose the ability to read.‘
  • From – http://en.wikipedia.org/wiki/Alexia_(acquired_dyslexia)

Alexithymia

• ‘A state of deficiency in understanding, processing, or describing emotions.‘
  • From – http://en.wikipedia.org/wiki/Alexithymia

Alice in Wonderland syndrome

• AKA – Todd’s syndrome
• ‘A disorienting neurological condition which affects human perception. Sufferers may experience micropsia, macropsia, and/or size distortion of other sensory modalities.‘
  • From – http://en.wikipedia.org/wiki/Alice_in_Wonderland_syndrome

Alien Hand Syndrome

• AKA – Anarchic Hand or Dr Strangelove Syndrome
• ‘An unusual neurological disorder in which one of the sufferer’s hands seem to take on a mind of its own.‘
  • From – http://en.wikipedia.org/wiki/Alien_Hand_Syndrome

Allochiria

• ‘A neurological disorder in which the patient responds to stimuli presented to one side of their body as if the stimuli had been presented at the opposite side.‘
  • From – http://en.wikipedia.org/wiki/Allochiria

Amusia

• ‘A musical disorder that appears mainly as a defect in processing pitch, but it also encompasses musical memory and recognition.‘
  • From – http://en.wikipedia.org/wiki/Amusia

• Case Study I

  • Title – Broca’s Amusica
  • Notes – Loss of musical abilities following a stroke; Describes a woman who selectively looses her ability to play the oboe.
  • Reference – Klawans, H. L. (1988). Toscanini’s fumble: And other tales of clinical neurology. Chicago, IL: Contemporary Books.

• Case Study II

  • Title – Things Fall Apart: Amusia and Dysharmonia
  • Notes – Describes people with ‘to whom a symphony sounds like the clattering of pots and pans‘.
  • Reference – Sacks, O. (2007). Musicophilia: Tales of Music and the Brain (First Edition). Alfred A. Knopf.
  • Video – https://youtu.be/tPRW0wZ9NOM

Anarchic Hand Syndrome

• See – Alien Hand Syndrome

Anomia

• ‘A severe problem with recalling words or names.’
  • From – http://en.wikipedia.org/wiki/Anomia

Anosognosia

• ‘condition in which a person who suffers disability seems unaware of or denies the existence of his or her disability. This may include unawareness of quite dramatic impairments, such as blindness or paralysis‘
  • From – http://en.wikipedia.org/wiki/Anosognosia

• Case Study

  • Title – The Sound of One Hand Clapping
  • Notes – Denial syndrome
  • Reference – Ramachandran, V.S., and Blakeslee, S. (1998). Phantoms in the brain: probing the mysteries of the human mind. New York, NY: William Morrow and Company, Inc.

Antero- and Retrograde Amnesia

• Categories – Memory
• ‘Anterograde amnesia is a loss of the ability to create new memories after the event that caused the amnesia, leading to a partial or complete inability to recall the recent past, while long term memories from before the event remain intact.” and “Retrograde amnesia is a form of amnesia where someone is unable to recall events that occurred before the development of the amnesia.’
  • From – http://en.wikipedia.org/wiki/Anterograde_Amnesia

• Case Study I

  • Title – The Last Hippie
  • Notes – Addresses several other issues: pituitary tumors, religion, anosognosia. May interest fans of 60’s rock music.
  • Reference – Sacks, O. (1995). An anthropologist on mars. New York, NY: Vintage Books.

• Case Study II

  • Title – Marooned in the Moment: H.M. a Case of Global Amnesia
  • Notes – Case of Henry Gustav Molaison (i.e., H.M.), who was “a memory-impaired patient who was widely studied from the late 1950s until his death. His case played a very important role in the development of theories that explain the link between brain function and memory, and in the development of cognitive neuropsychology, a branch of psychology that aims to understand how the structure and function of the brain relates to specific psychological processes.” This case study has a qualitative twist.
  • Reference – Ogden, J. A. (2005). Fractured minds. New York, NY: Oxford University Press.
• See also – Korsakoff’s syndrome

Anton–Babinski Syndrome

• ‘People who suffer from it are “cortically blind”, but affirm, often quite adamantly and in the face of clear evidence of their blindness, that they are capable of seeing.’
  • From – http://en.wikipedia.org/wiki/Anton%E2%80%93Babinski_syndrome

Aphasia

• ‘An acquired language disorder in which there is an impairment of any language modality.‘
  • From – http://en.wikipedia.org/wiki/Aphasia

• Case Study

  • Title – Defending the Cavewoman (Chapter 1)
  • Notes – Language acquisition (from the perspective of early abuse) with an eye on evolution.
  • Reference – Klawans, H. L. (2000). Strange behavior: Tales of evolutionary neurology. New York, NY: W.W. Norton & Company.

Aprosodia

• ‘A neurological condition characterized by the inability of a person to properly convey and/or interpret emotional prosody.’
  • From – http://en.wikipedia.org/wiki/Aprosodia

Autism Spectrum Disorder and Aspergers

• ‘The autism spectrum disorders is a spectrum of psychological conditions characterized by widespread abnormalities of social interactions and communication, as well as severely restricted interests and highly repetitive behavior.” and “Asperger’s syndrome is an autism spectrum disorder that is characterized by significant difficulties in social interaction, along with restricted and repetitive patterns of behavior and interests. It differs from other autism spectrum disorders by its relative preservation of linguistic and cognitive development.‘
  • From – http://en.wikipedia.org/wiki/Autism_spectrum

• Case Study I

  • Title – An Anthropologist on Mars
  • Notes – Extremely insightful look at autism from within
  • Reference – Sacks, O. (1995). An anthropologist on mars. New York, NY: Vintage Books.

• Case Study II

  • Title – Inside the Mind of a Savant
  • Notes – Case of Kim Peek, the inspiration for the movie “Rain Man”
  • Reference – Treffert, D. A., & Christensen, D. D. (2006). Inside the Mind of a Savant. Scientific American.

• Case Study III

  • Title -Prodigies
  • Notes – Chronicles an artistic savant
  • Reference – Sacks, O. (1995). An anthropologist on mars. New York, NY: Vintage Books.

• Case Study IV

  • Title – The Surfing Savant
  • Notes – Compelling story of how Pro surfer’s Asperger’s symptoms both help and hinder him.
  • Reference – Solotaroff, P (2010) The Surfing Savant. Rolling Stone. Issue 1102, April 15, 2010
• More links
  • http://en.wikipedia.org/wiki/Aspergers
  • http://en.wikipedia.org/wiki/Savant_syndrome
  • http://en.wikipedia.org/wiki/Historical_figures_sometimes_considered_autistic

Autotopagnosia

• ‘Is agnosia that affects the sense of posture; characterized by an inability to localize and orient different parts of the body.‘
  • From – http://en.wikipedia.org/wiki/Autotopagnosia

• Case Study

  • Title – A Body in the Mind: A Case of Autotopagnosia
  • Notes – Gerstmann’s Syndrome; Covers a variety of often related perceptual deficits
  • Reference – Ogden, J. A. (2005). Fractured minds. New York, NY: Oxford University Press.
• See also – http://en.wikipedia.org/wiki/Gerstmann_syndrome

Balint’s Syndrome

• ‘Characterized by optic ataxia (incoordination of hand and eye movement), oculomotor apraxia (the inability to voluntarily guide eye movements/ change to a new location of visual fixation), and simultanagnosia (the inability to perceive more than one object at a time, even when in the same place).‘
  • From – http://en.wikipedia.org/wiki/Balint’s_syndrome

Blindsight

• ‘A phenomenon in which people who are perceptually blind in a certain area of their visual field demonstrate some response to visual stimuli.‘
  • From – http://en.wikipedia.org/wiki/Blindsight

Capgras Delusion

• ‘A disorder in which a person holds a delusion that a friend, spouse, parent or other close family member has been replaced by an identical-looking impostor. The Capgras delusion is classed as a delusional misidentification syndrome, a class of delusional beliefs that involves the misidentification of people, places, or objects. It can occur in acute, transient, or chronic forms.‘
  • From – http://en.wikipedia.org/wiki/Capgras_delusion

• Case Study

  • Title – The Unbearable Likeness of Being
  • Notes – Provides insight into the link between visual recognition and emotion
  • Reference – Ramachandran, V.S., and Blakeslee, S. (1998). Phantoms in the brain: probing the mysteries of the human mind. New York, NY: William Morrow and Company, Inc.

Cerebral Achromatopsia

• ‘A type of color-blindness that is caused by damage to the cerebral cortex of the brain, rather than abnormalities in the cells of the eye’s retina.‘
  • From – http://en.wikipedia.org/wiki/Cerebral_achromatopsia

Charles Bonnet Syndrome

• ‘A condition that causes patients with visual loss to have complex visual hallucinations.‘
  • From – http://en.wikipedia.org/wiki/Charles_Bonnet_Syndrome

• Case Study

  • Title – The Secret Life of James Thurber
  • Notes – Visual hallucinations in the blind
  • Reference – Ramachandran, V.S., and Blakeslee, S. (1998). Phantoms in the brain: probing the mysteries of the human mind. New York, NY: William Morrow and Company, Inc.

Conduction Aphasia

• AKA – Associative Aphasia
• ‘An acquired language disorder, it is characterized by intact auditory comprehension, fluent (yet paraphasic) speech production, but poor speech repetition.‘
  • From – http://en.wikipedia.org/wiki/Conduction_aphasia

Cotard Delusion or Syndrome

• AKA – Walking Corpse Syndrome
• ‘A rare neuropsychiatric disorder in which people hold a delusional belief that they are dead (either figuratively or literally), do not exist, are putrefying, or have lost their blood or internal organs. Rarely, it can include delusions of immortality.‘
  • From – http://en.wikipedia.org/wiki/Cotard_Delusion

Discalculia

• ‘A specific [developmental] learning disability or difficulty involving… difficulty in learning or comprehending mathematics.‘
  • From – http://en.wikipedia.org/wiki/Discalculia

Dr Strangelove Syndrome

• See – Alien Hand Syndrome

Dysprosody

• ‘Also known as pseudo-foreign dialect syndrome, refers to a disorder in which one or more of these prosodic functions are either compromised or eliminated completely.‘
  • From – http://en.wikipedia.org/wiki/Dysprosody

Encephalitis Lethargica

• ‘The disease attacks the brain, leaving some victims in a statue-like condition, speechless and motionless.‘
  • From – https://en.wikipedia.org/wiki/Encephalitis_lethargica

• Case Study

  • Title – Awakenings
  • Notes – ‘They would be conscious and aware – yet not fully awake; they would sit motionless and speechless all day in their chairs, totally lacking energy, impetus, initiative, motive, appetite, affect or desire; they registered what went on about them without active attention, and with profound indifference. They neither conveyed nor felt the feeling of life; they were as insubstantial as ghosts, and as passive as zombies.‘
  • Reference – Sacks, O. (1990). Awakenings. HarperPerennial.

Expressive or Broca’s Aphasia

• ‘Is characterized by the loss of the ability to produce language (spoken or written).‘
  • From – http://en.wikipedia.org/wiki/Expressive_aphasia

• Case Study

  • Title – The Breakdown of Language: Case Studies of Aphasia
  • Notes – Two cases illustrate Broca’s and Wernicke’s aphasia, extensive background information
  • Reference – Ogden, J. A. (2005). Fractured minds. New York, NY: Oxford University Press.

Foreign Accent Syndrome

• ‘To the untrained ear, those with the syndrome sound as though they speak their native languages with a foreign accent.‘
  • From – http://en.wikipedia.org/wiki/Foreign_Accent_Syndrome

Fregoli Delusion

• ‘A rare disorder in which a person holds a delusional belief that different people are in fact a single person who changes appearance or is in disguise.‘
  • From – http://en.wikipedia.org/wiki/Fregoli_delusion

Gaze-Evoked Tinnitus

• ‘Hear a ringing sound when looking to the left (or right).‘
  • From – Coad ML, Lockwood A, Salvi R, Burkard R. (2001). Characteristics of patients with gaze-evoked tinnitus. Otol Neurotol. 22(5):650-4.

Hemiplegia

• ‘A condition in which the limbs on one side of the body have severe weakness. Hemiplegia is more severe than hemiparesis, wherein one half of the body has less marked weakness.[1]Hemiplegia may be congenital or acquired from an illness or stroke.‘
  • From – http://en.wikipedia.org/wiki/Hemiplegia

• Case Study I

  • Title – My Mother’s Best Friend (Chapter 1)
  • Notes – Anosognosia; Also touches on strokes and aphasia.
  • Reference – Klawans, H. L. (1990). Newton’s madness: Further tales of clinical neurology. New York, NY: Harper and Row Publishers.

• Case Study II

  • Title – The Man Who Fell Out of Bed
  • Notes – Anosognosia; Very short, lacking recent background information
  • Reference – Sacks, O. (1985). The man who mistook his wife for a hat and other clinical tales. New York, NY: Harper and Row Publishers.

Hemispatial Neglect

• ‘A condition in which, after damage to one hemisphere of the brain, a deficit in attention to and awareness of one side of space is observed.‘
  • From – http://en.wikipedia.org/wiki/Hemispatial_neglect

• Case Study I

  • Title – Out of mind, out of sight: a case of hemineglect
  • Notes – Covers topic in great depth.
  • Reference – Ogden, J. A. (2005). Fractured minds. New York, NY: Oxford University Press.

• Case Study II

  • Title – Through the Looking Glass
  • Reference – Ramachandran, V.S., and Blakeslee, S. (1998). Phantoms in the brain: probing the mysteries of the human mind. New York, NY: William Morrow and Company, Inc.
• Other links
  • A dog with unilateral neglect: https://youtu.be/hHo-y7WJIlU

 

Huntington’s Disease

• ‘A progressive neurodegenerative genetic disorder, which affects muscle coordination and leads to cognitive decline and dementia. It typically becomes noticeable in middle age. HD is the most common genetic cause of abnormal involuntary writhing movements called chorea and is much more common in people of Western European descent than in those from Asia or Africa.‘
  • From – http://en.wikipedia.org/wiki/Huntington’s_disease

• Case Study I

  • Title – Anticipation
  • Notes – Lacking most recent information
  • Reference – Klawans, H. L. (2000). Strange behavior: Tales of evolutionary neurology. New York, NY: W.W. Norton & Company.

• Case Study II

  • Title – Huntington’s Disease: A Family Challenged
  • Notes – Chronicles the struggle of a family with Huntington’s disease, extensive background information.
  • Reference – Ogden, J. A. (2005). Fractured minds. New York, NY: Oxford University Press.

• Case Study III

  • Title – Spontaneous Generation
  • Notes – Genetics and Huntington’s disease, lacking most recent information.
  • Reference – Klawans, H. L. (1988). Toscanini’s fumble: And other tales of clinical neurology. Chicago, IL: Contemporary Books.

Hyperlexia

• ‘It can be viewed as a superability in which word recognition ability goes far above expected levels of skill.‘
  • From – http://en.wikipedia.org/wiki/Hyperlexia

Ideomotor Apraxia

• ‘A neurological disorder characterized by the inability to correctly imitate hand gestures and voluntarily pantomime tool use, e.g. pretend to brush one’s hair.‘
  • From – http://en.wikipedia.org/wiki/Ideomotor_apraxia

Jumping Frenchmen of Maine

• ‘It results in an exaggerated “startle” reflex.. for instance, individuals who would obey any command given suddenly, even if it meant striking a loved one, and repeat back unfamiliar or foreign phrases uncontrollably.‘
  • From – http://en.wikipedia.org/wiki/Jumping_Frenchmen_of_Maine

Korsakoff’s Syndrome

• Category – Memory
• ‘a neurological disorder caused by the lack of thiamine (vitamin B1) in the brain… There are six major symptoms of Korsakoff’s syndrome: 1) anterograde amnesia; 2) retrograde amnesia; 3) confabulation, that is, invented memories which are then taken as true due to gaps in memory sometimes associated with blackouts; 4) meager content in conversation; 5) lack of insight; and 6) apathy.’
  • From – http://en.wikipedia.org/wiki/Korsakoff’s_syndrome

• Case Study I

• Title – The Lost Mariner
• Notes – Lacking recent background information
• Reference – Sacks, O. (1985). The man who mistook his wife for a hat and other clinical tales. New York, NY: Harper and Row Publishers.

• Case Study II

  • Title – Morbid Obesity
  • Notes – Case of Korsakoff’s syndrome after gastric bypass surgery.
  • Reference – Klawans, H. L. (1990). Newton’s madness: Further tales of clinical neurology. New York, NY: Harper and Row Publishers.
• See also – Anterograde and Retrograde Amnesia

King-Kopetzky Syndrome

• ‘Difficulty in hearing speech in the presence of background noise. This is in conjunction with the finding of normal hearing test results.‘
  • From – http://en.wikipedia.org/wiki/King-Kopetzky_syndrome

Kluver-Bucy Syndrome

• ‘Symptoms.. included are… Docility; Dietary changes; Hyperorality; Hypersexuality; Visual agnosia.‘
  • From – http://en.wikipedia.org/wiki/Kluver-Bucy_Syndrome

Macropsia

• AKA – Megalopia
• ‘A neurological condition affecting human visual perception, in which objects within an affected section of the visual field appear larger than normal, causing the subject to feel smaller.‘
  • From – http://en.wikipedia.org/wiki/Macropsia

Megalopia

• See – Macropsia

Micropsia

• ‘A condition affecting human visual perception in which objects are perceived to be smaller than they actually are.‘
  • From – http://en.wikipedia.org/wiki/Micropsia

Motion Blindness

• See – Akinetopsia

Multiple sclerosis or MS

• ‘is a disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading to demyelination and scarring as well as a broad spectrum of signs and symptoms… The person with MS can suffer almost any neurological symptom or sign, including changes in sensation (hypoesthesia and paraesthesia), muscle weakness, muscle spasms, or difficulty in moving; difficulties with coordination and balance (ataxia); problems in speech (dysarthria) or swallowing (dysphagia), visual problems (nystagmus, optic neuritis, or diplopia), fatigue, acute or chronic pain, and bladder and bowel difficulties. Cognitive impairment of varying degrees and emotional symptoms of depression or unstable mood are also common.[1] Uhthoff’s phenomenon, an exacerbation of extant symptoms due to an exposure to higher than usual ambient temperatures, and Lhermitte’s sign, an electrical sensation that runs down the back when bending the neck, are particularly characteristic of MS although not specific.‘
  • From – http://en.wikipedia.org/wiki/Multiple_sclerosis

• Case Study I

  • Title – The Bobbsey Twins Take Neurology
  • Notes – Covers its motor and perceptual nature
  • Reference – Klawans, H. L. (1990). Newton’s madness: Further tales of clinical neurology. New York, NY: Harper and Row Publishers.

• Case Study II

  • Title – Tomorrow is Another Day: Living with Multiple Sclerosis
  • Notes – Describes case of a woman and illustrates the variable nature of this disorder
  • Reference – Ogden, J. A. (2005). Fractured minds. New York, NY: Oxford University Press.

Paraphasia

• ‘A feature of aphasia in which one loses the ability of speaking correctly, substitutes one word for another, and changes words and sentences in an inappropriate way.‘
  • From – http://en.wikipedia.org/wiki/Paraphasia

Parkinson’s disease

• ‘A degenerative disorder of the central nervous system that often impairs the sufferer’s motor skills, speech, and other functions.‘
  • From – http://en.wikipedia.org/wiki/Parkinsons

• Case Study I

  • Title – Mind Over Matter: Coping with Parkinson’s Disease
  • Notes – Describes case of a medical doctor with Parkinson’s disease, pallidotomy, extensive background information.
  • Reference – Ogden, J. A. (2005). Fractured minds. New York, NY: Oxford University Press.

• Case Study II

  • Title – The Lizard
  • Notes – Covers treatment with L-dopa and adrenal transplants.
  • Reference – Klawans, H. L. (1990). Newton’s madness: Further tales of clinical neurology. New York, NY: Harper and Row Publishers.

Phantom Limb

• ‘Is the sensation that an amputated or missing limb (even an organ, like the appendix) is still attached to the body and is moving appropriately with other body parts.[1][2][3] Approximately 60 to 80% of individuals with an amputation experience phantom sensations in their amputated limb, and the majority of the sensations are painful.[4] Phantom sensations may also occur after the removal of body parts other than the limbs, e.g. after amputation of the breast, extraction of a tooth (phantom tooth pain) or removal of an eye (phantom eye syndrome). The missing limb often feels shorter and may feel as if it is in a distorted and painful position.‘
  • From – http://en.wikipedia.org/wiki/Phantom_Limb

• Case Study

  • Title – The Phantom Within (Chapter 1); Knowing Where to Scratch (Chapter 2) and; Chasing the Phantom (Chaper 3)
  • Notes – Tale tracing phantom limbs to neural plasticity.
  • Reference – Ramachandran, V.S., and Blakeslee, S. (1998). Phantoms in the brain: probing the mysteries of the human mind. New York, NY: William Morrow and Company, Inc.

Pragmatic language impairment

• ‘People with these impairments have special challenges with the semantic aspect of language (the meaning of what is being said) and the pragmatics of language (using language appropriately in social situations).‘
  • From – http://en.wikipedia.org/wiki/Pragmatic_language_impairment

Prosopagnosia

• ‘A disorder of face perception where the ability to recognize faces is impaired, while the ability to recognize other objects may be relatively intact.‘
  • From – http://en.wikipedia.org/wiki/Prosopagnosia

Pure Word Deafness

• ‘Inability to comprehend the meaning of speech, but (in most cases) still being able to hear, speak, read, and write.‘
  • From – http://en.wikipedia.org/wiki/Pure_Word_Deafness

Receptive or Wernicke’s Aphasia

• ‘Speech is preserved, but language content is incorrect.‘
  • From – http://en.wikipedia.org/wiki/Receptive_aphasia

• Case Study

  • Title – The Breakdown of Language: Case Studies of Aphasia
  • Notes – Two cases illustrate Broca’s and Wernicke’s aphasia, extensive background information
  • Reference – Ogden, J. A. (2005). Fractured minds. New York, NY: Oxford University Press.

Reduplicative Paramnesia

• ‘Is the delusional belief that a place or location has been duplicated, existing in two or more places simultaneously, or that it has been ‘relocated’ to another site.‘
  • From – http://en.wikipedia.org/wiki/Reduplicative_paramnesia

Schizophrenia

• ‘A severe mental illness characterized by a disintegration of the process of thinking, of contact with reality, and of emotional responsiveness. It most commonly manifests as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking with significant social or occupational dysfunction.‘
  • From – http://en.wikipedia.org/wiki/Schizophrenia

Somatoparaphrenia

• ‘A type of monothematic delusion where one denies ownership of a limb or an entire side of one’s body.‘
  • From – http://en.wikipedia.org/wiki/Somatoparaphrenia

Synesthesia

• ‘A neurologically-based condition in which stimulation of one sensory or cognitive pathway leads to automatic, involuntary experiences in a second sensory or cognitive pathway.‘
  • From – http://en.wikipedia.org/wiki/Synesthesia

• Case Study

  • Title – The Man Who Tasted Shapes
  • Notes – This book contains many case studies on synesthesia
  • Reference – Cytowic, R. E. (2003). The man who tasted shapes. Cambridge, MA: MIT Press.
• Other links
  • https://youtu.be/eHnnGHgeyC0

Text Blindness

• See – Alexia

Todd’s syndrome

• See – Alice in Wonderland syndrome

Tourette’s Syndrome

• Category – Motor
• ‘Characterized by multiple physical (motor) tics and at least one vocal (phonic) tic.‘
  • From – http://en.wikipedia.org/wiki/Tourette’s_Syndrome

• Case Study I

  • Title – A Surgeon’s Life
  • Notes – Great success in the face of adversity.
  • Reference – Sacks, O. (1995). An anthropologist on mars. New York, NY: Vintage Books.

• Case Study II

  • Title – Just right: Mahmoud Abdul-Rauf
  • Notes – Describes case of professional basketball player with the disorder.
  • Reference – Klawans, H. L. (1996). Why Michael couldn’t hit: and other tales of the neurology of sports. New York, NY: W.H. Freeman.

• Case Study III

  • Title – Witty Ticcy Ray
  • Notes – Lacking recent background information
  • Reference – Sacks, O. (1985). The man who mistook his wife for a hat and other clinical tales. New York, NY: Harper and Row Publishers.
• Other links
  • https://youtu.be/KtCG0wG-5E0

Walking Corpse Syndrome

• See – Cotard’s Delusion

Visual Agnosia

• ‘The inability of the brain to make sense of or make use of some part of otherwise normal visual stimulus and is typified by the inability to recognize familiar objects or faces.‘
  • From – http://en.wikipedia.org/wiki/Visual_agnosia

Visual Aphasia

• See – Alexia

Williams Syndrome

• ‘A distinctive, “elfin” facial appearance, along with a low nasal bridge; an unusually cheerful demeanor and ease with strangers; developmental delay coupled with unusual (for persons who are diagnosed as developmentally delayed) language skills; and cardiovascular problems, such as supravalvular aortic stenosis and transient hypercalcaemia.‘
  • From – http://en.wikipedia.org/wiki/Williams_Syndrome

Wilson’s Disease

• ‘An autosomal recessive genetic disorder in which copper accumulates in tissues… about half the patients with Wilson’s have neurological or psychiatric problems. Most patients initially have mild cognitive deterioration and clumsiness, as well as changes in behavior. Specific neurological symptoms then follow, often in the form of parkinsonism (increased rigidity and slowing of routine movements) with or without a typical hand tremor, masked facial expressions, slurred speech, ataxia (lack of coordination) or dystonia (twisting and repetitive movements of part of the body).‘
  • From – http://en.wikipedia.org/wiki/Wilson’s_disease

• Case Study

  • Title – Still Smiling (Chapter 2)
  • Notes – Genetic disorder – copper metabolism.
  • Reference – Klawans, H. L. (1990). Newton’s madness: Further tales of clinical neurology. New York, NY: Harper and Row Publishers.

Word Blindness

• See – Alexia